DID WE FIND A CURE? photo by Polina Tankilevitch - Pexels This was published on YouTube on March 27th 2020 The text from this video: Hydroxychloroquine, Chloroquine and Remdesivir: The Coronavirus Cure? Hydroxychloroquine, Chloroquine and Remdesivir are medications being used to potentially treat and cure coronavirus (COVID-19). Hydroxychloroquine (Plaquenil) and its derivative chloroquine, are anti-malarial drugs that were found to effective in previous coronavirus outbreaks with SARS in 2002. Remdesivir is a broadspectrum antiviral that was developed to treat Ebola and was found in animal studies to be effective against coronavirus. Researchers are adding the antibiotic azithromycin with hydroxychloroquine to treat coronavirus but this is unclear as to why. It is believed that chloroquine works by inhibiting coronavirus from invading your cells by changing the configuration of the ACE2 receptor on your cell and the spike protein on coronavirus. Chinese researchers showed in lab tests that hydroxychloroquine can slow infections from coronavirus by blocking the ACE2 receptors on your cells. Remdesivir, developed by Gilead Sciences Inc., is an investigational broad-spectrum antiviral treatment that was previously tested in humans with Ebola and had shown promise in animal models for treating Middle East respiratory syndrome (MERS) and severe acute respiratory syndrome (SARS), which are caused by other coronaviruses. Remdesivir doesn’t target the virus itself. Researchers have discovered that it targets the system the virus uses to replicate itself by mimicking the genetic code for the viral RNA, adenosine. When it comes time for your body’s polymerase enzyme to copy the viral genetic code, it starts making the wrong code because remdesivir has tricked the enzyme into believing it is adenosine. So now when the viral tries to use your body’s polymerase enzyme, it will make the wrong genetic code and thus the virus cannot replicate or infect other cells. So while there are many more medications being studied and investigated to treat coronavirus, hydroxychloroquine and remdesivir are the two drugs mentioned more and more because of previous research for other infections and illnesses. It is obvious a lot more research needs to be done and nothing conclusive will be available anytime soon. - Dr. Yo How Does Coronavirus Affect The Body? One of the questions and the answer by Dr. Yo I found interesting and worth mentioning: Question: Good info Dr., thank you. Here's the question: If you contracted community pneumonia secondary to COVID19, and didn't have access to a hospital (either because of cost or intentionally to avoid an additional risk), would you take either of these medications, assuming you no contraindications? Thank you. Answer by Dr. Yo: Thank you for the comments. Wow that is a very tough question. So first off you have to look at this as 2 different infections: the bacterial pneumonia would most likely be treated with antibiotics. Now I am assuming your question is specifically asking if I would take either hydroxychloroquine or remdesivir to treat a COVID-19 infection- it really depends on how severe my infection were. Remember 80-85% of COVID-19 cases are mild symptoms meaning a fever, dry cough, muscle aches. In connection with this, Dr. Seheult at about 4:50 speaks about testing these treatments in his video April 2nd 2020 Post-exposure Prophylaxis or Preemptive Treatment for SARS-Coronavirus-2 Hydroxychloroquine Treatment Trial conducted by the University of Minnesota Information https://covidpep.umn.edu/ (seeking participants from the United States and Canada, please consider if you qualify). More about this: March 24th 2020: Clinical drug trials starting in Europe include potential of chloroquine to treat coronavirus Europe has begun clinical trials of experimental drugs to treat COVID-19 in thousands of patients including a much talked about antimalarial drug, chloroquine. The trials will include 3,200 patients in the Netherlands, Belgium, Luxembourg, the United Kingdom, France, and Spain. There will be 800 patients in France, where clinical trials were launched this past weekend. .............. READ MORE CAUTIONPlease be careful, do not self-medicate, but seek professional help! On March 19th, ABC News video: Trump touts chloroquine, old malaria drug that doctors say may help treat coronavirus On March 24th the New York Times reported: Man Fatally Poisons Himself While Self-Medicating for Coronavirus, Doctor Says UPDATE TO THE THEME OF CHLOROQUINE April 6th 2020 On a search I found this very interesting article: No, cinchona bark is not a cure for coronavirus  Posts touting the curative effects of cinchona, or fever tree, bark have recently been circulating on social networks such as Instagram and Facebook. These posts promise a “natural” source of the prescription-only drug chloroquine. ..... READ MORE The bottom line: Cinchona is highly toxic and self-medication with it or any other unproven cures should be avoided. Protect your health and don’t waste money funding unethical people and companies profiteering off fear in these uncertain times.
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